Kinetics and mechanism of the hydrolysis of N-methylparanitroacetanilide and N-methylmetanitroacetanilide in aqueous solutions of potassium hydroxide

Abstract

1. The kinetic principles of the hydrolysis of N-methylmetanitroacetanilide and N-methylparanitroacetanilide in aqueous solutions of potassium hydroxide were studied by a spectrophotometric method at 25°. 2. The investigated anilides exist in aqueous solutions of potassium hydroxide in three forms: non-ionized, singly ionized, and doubly ionized. The effective rate constant is determined by the relative concentrations of the singly and doubly ionized forms. 3. The true rate constants of hydrolysis and the equilibrium constants of the formation of the singly ionized form of N-methylmetanitroacetanilide and N-methylparanitroacetanilide were calculated.