Abstract
Isolation of a Multi-Drug Resistant and Kpc Positive Salmonella Group E from a Patient with Severe Combined Immunodeficiency
Highlights
Salmonella infection typhoid fever is common among developing countries; it causes a wide variety of infection like intestinal and extra intestinal Salmonellosis
ESCMID and CLSI recommend only a few antibiotics to be tested against Salmonella typhi and Salmonella non-typhi
Ampicillin, Co-trimoxazole, a flouroquinolone and a 3rd generation Cephalosporin antibiotics in cases of extra intestinal Salmonellosis must be reported in the sensitivity panel
Summary
The investigators were able to isolate the first Salmonella non-typhi (Group E) that is highly resistant to Carbepenms, Cephalosporins & other anti-Salmonella drugs. Ampicillin, Co-trimoxazole, a Flouroquinolone and a 3rd generation Cephalosporin antbiotic in cases of extra intestinal Salmonellosis must be reported in the sensitivity panel. This case reports the 1st strain of Salmonella Group E that is highly resistant to these Anti-microbials including Carbapenems and responded only to Colistin. Discourages the use of the MHT in detecting Carbapenamase. Both EUCAST and CLSI recommended Molecular Biology in detecting Carbapenemase and their respective class
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