Intelligent identification and classification of diabetic retinopathy using fuzzy inference system

Abstract

ABSTRACT Background and Objective Persistent diabetes results in diabetic retinopathy (DR), affecting the retinal blood vessels (BVs), causing lesions. Rapid identification and treatment are crucial for preventing vision loss. Low ophthalmologist to patient’s ratio results automating the DR detection a dire need. Therefore, a feature extraction method is proposed using a Mamdani fuzzy inference system (FIS) classifier for efficient identification. Methods Mathematical morphology, region growth, and 12-region search computation have been used to mask the BVs and macula. The masked green plane image was subjected to Nick's thresholding to locate the dark lesions, from which statistical features were extracted and employed in the Mamdani FIS to classify the DR. Results On evaluating a total of 909 images from the MESSIDOR database shows, average sensitivity, specificity, area under the curve receiver operating characteristics, and accuracy of 99.7%, 99.8%, 99.4%, and 99.6%, respectively. The algorithm performs well in real-time images from two local hospitals. Conclusion The proposed technique provides a powerful yet flexible tool for improving the diagnosis and treatment of this condition that threatens vision, as it combines the strengths of fuzzy logic, clinical knowledge, and adaptive learning to provide precise, timely, non-invasive, and economical solutions.