Influences of magnesium sulfate and nifedipine controlled release tablet on the blood pressure, renal function and prognosis of infant and mum of pregnancy induced hypertension patients

Abstract

Objective To investigate the influences of magnesium sulfate and nifedipine controlled release tablet on the blood pressure, renal function and prognosis of infant and mum of pregnancy induced hypertension patients. Methods Fifty-two pregnancy induced hypertension patients admitted by Xiaoyi of Traditional Chinese Medicine from March 2016 to April 2017 were divide into control group and research group according to random number table method. The control group was given magnesium sulfate and the research group was given magnesium sulfate and nifedipine controlled release tablet. The blood pressure, renal function, haemodynamics and side effects of the two groups were compared. Results Before treatment, there was no significant difference in blood pressure, renal function or hemodynamics between the two groups (P>0.05). After treatment, the improvement of blood pressure, renal function and hemodynamics in study group were better than those in control group (P<0.05). The incidence of adverse reactions in study group was less than that in control group (P<0.05). Conclusions The combination of magnesium sulfate and nifedipine controlled release tablet has better curative effects on pregnancy induced hypertension patients. It can effectively improve the renal function, haemodynamics, blood pressure and prognosis of patients and is worth clinical promotion and application. Key words: Pregnancy induced hypertension; Magnesium sulfate; Nifedipine controlled release tablet; Renal function; Hemodynamics