Influence of percutaneous coronary intervention on T-wave peak-end interval in coronary heart disease patients and its warning value on sudden cardiac death

Abstract

Objective To investigate the influence of percutaneous coronary intervention on T-wave peak-to-interval and its value of early warning of sudden cardiac death in patients with coronary artery disease. Methods From January 2013 to December 2014, 90 patients with coronary heart disease who underwent percutaneous coronary intervention in the Second Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine were selected as observation group.And at the same time, 90 patients with normal coronary angiography in our hospital were selected as control group.Tp-Te (T-wave peak to end-time limit in ECG) and Tp-Te/QT (Tp-Te) were compared between the observation group and the control group.The ratio of the period to the QT interval, Tp-Te/ (heart rate corrected T-peak period), Tp-Te, Tp-Te/QT, Tp-Te/ before and after treatment in the observation group, and treatment Tp-Te, Tp-Te/QT, Tp-Te/ in the group with and without ventricular arrhythmia and sudden cardiac death were observed. Results Before treatment, the Tp-Te[(116.47±26.81)ms], Tp-Te/QT[(0.29±0.06)] and Tp-Te/[(131.78±36.23)ms] in the observation group were higher than those in the control group -Te(78.69±22.73)ms, Tp-Te/QT (0.21±0.04), Tp-Te/ (100.49±32.96)ms] (t=10.197, 10.525, 6.061, all P<0.05). After treatment, the Tp-Te[(94.78±11.34)ms], Tp-Te/QT[(0.24±0.04)], Tp-Te/[(108.62±20.18)ms] in the observation group were lower than those before treatment (t=7.069, 6.558, 5.298, all P<0.05). At 6 months after operation, the Tp-Te and Tp-Te/ were significantly lower than postoperative 24h[(99.89±21.64)ms, (117.35±32.47)ms](t=1.984, 2.166, all P<0.05). After treatment, the Tp-Te[(118.87±30.92)ms], Tp-Te/QT [(0.29±0.08)], and Tp-Te/[(135.73±37.29)ms] in ventricular arrhythmia patients with sudden cardiac death were higher than those without sudden cardiac death[(95.13±26.38)ms, (0.25±0.06), (106.36±30.14)ms] (t=3.012, 2.171, 3.226, all P<0.05). Conclusion T-Te, Tp-Te/QT, Tp-Te/ T-peak peak-to-interphase indicators can be used to predict the degree of coronary artery ischemia and disease, but also for cardiovascular diseases such as ventricular arrhythmias and sudden cardiac death.The index adverse events play a certain role in early warning and have clinical research value. Key words: Percutaneous coronary intervention; Coronary disease; T-wave peak end-stage