Abstract
We report here the complete genome sequence of a triple-reassortant H1N1 swine influenza virus strain, A/swine/Guangxi/BB1/2013 (H1N1) (GXBB1), isolated from a swine in the Guangxi Province of southern China in 2013. We obtained the complete genome sequence of the GXBB1 virus. Sequence analysis demonstrated that this H1N1 virus was a triple-reassortant swine influenza virus (SIV) whose genes originated from avian, human, and swine, respectively. Knowledge regarding the complete genome sequence of the GXBB1 virus will be useful for epidemiological surveillance.
Highlights
We report here the complete genome sequence of a triple-reassortant H1N1 swine influenza virus strain, A/swine/Guangxi/BB1/ 2013 (H1N1) (GXBB1), isolated from a swine in the Guangxi Province of southern China in 2013
It has been reported that some new variants were generated by reassortment between avian and human viruses that occurred in pigs in nature [3, 4, 5], and the new variants have the potential to pose a serious threat to public health
Phylogenetic analysis showed that the HA, NA, and M genes belonged to the European avian lineage
Summary
We report here the complete genome sequence of a triple-reassortant H1N1 swine influenza virus strain, A/swine/Guangxi/BB1/ 2013 (H1N1) (GXBB1), isolated from a swine in the Guangxi Province of southern China in 2013. Swine influenza virus (SIV), a member of the genus Orthomyxovirus (family Orthomyxoviridae), is a single-stranded, negativesense RNA virus that causes an acute and highly contagious respiratory disease in swine. The pig can serve as a mixing vessel for the generation of genetically reassortant viruses because the porcine tracheal cells have receptors for both avian and human influenza viruses [1, 2]. It has been reported that some new variants were generated by reassortment between avian and human viruses that occurred in pigs in nature [3, 4, 5], and the new variants have the potential to pose a serious threat to public health.
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