Abstract

Thannhauser has divided the xanthomatoses associated with altered blood lipids into two main groups: (1) hypercholesteremic xanthomatoses and (2) hyperlipemic xanthomatoses. In the first group, the fasting blood serum is clear; in the second group the serum is milky or chylous. The entities described in the hyperlipemic group (2) are the following: A. Idiopathic hyperlipemia with secondary xanthoma Idiopathic (familial) hyperlipemia in children with hepatosplenomegaly and secondary xanthoma Idiopathic hyperlipemia in adults with secondary xanthomas occasionally accompanied by glycosuria and hepatosplenomegaly B. Syptomatic hyperlipemia with secondary eruptive xanthoma Xanthoma diabeticorum Hyperlipemia in chronic pancreatitis and eruptive xanthoma Hyperlipemia in glycogen storage disease (von Gierke's disease) and eruptive xanthoma Hyperlipemia in lipid nephrosis It has been pointed out by Thannhauser that xanthomatosis has never been reported in association with the hyperlipemia of lipid nephrosis or the nephrotic stage of glomerulonephritis. A recent search through the

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