Abstract

ABSTRACTWe report for the first time in the United States the identification of a swine pasivirus (SPaV) strain with a genomic sequence identity of less than 80% to other SPaVs reported in Europe and China, using a next-generation sequencing (NGS) technique in sow tissues collected from an animal study conducted in 2001, suggesting virus circulation in domestic swine.

Highlights

  • An almost full-length pasivirus genome of 6,695 nucleotides was obtained from a sow tissue pool

  • The virus strain was designated as swine pasivirus type 1 (SPaV1)/US/1750816IA60467-1/2001

  • Analysis of the US SPaV1 sequence demonstrated that the virus has a genomic organization similar to that of prototype SPaV1

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Summary

Introduction

We report for the first time in the United States the identification of a swine pasivirus (SPaV) strain with a genomic sequence identity of less than 80% to other SPaVs reported in Europe and China, using a next-generation sequencing (NGS) technique in sow tissues collected from an animal study conducted in 2001, suggesting virus circulation in domestic swine. An almost full-length pasivirus genome of 6,695 nucleotides was obtained from a sow tissue pool. The virus strain was designated as SPaV1/US/1750816IA60467-1/2001 (here, US SPaV1).

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