Abstract
We present draft genome sequences of 15 clinical Vibrio isolates of various serogroups. These are valuable data for use in studying Vibrio cholerae genetic diversity, epidemic potential, and strain attribution.
Highlights
Vibrio cholerae is a Gram-negative bacterium and the etiologic agent of cholera
Cholera epidemics are associated with specific serogroups, namely O1 and O139, the recent events in Haiti demonstrate an interesting exception (2)
It is currently not known why specific serogroups are associated with epidemic potential even though many other serogroups carry the major virulence factors
Summary
Vibrio cholerae is a Gram-negative bacterium and the etiologic agent of cholera. Cholera is endemic in regions with poor sanitation and can be a significant problem wherever local infrastructure is disrupted due to natural or human-caused disasters. V. cholerae strains can be classified into over 200 serogroups on the basis of differences in the surface-expressed O antigen. Cholera epidemics are associated with specific serogroups, namely O1 and O139, the recent events in Haiti demonstrate an interesting exception (2).
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