Abstract
Human rhinovirus (RV) isolates from the RV-C species are recently discovered infectious agents that are closely linked to asthma and wheezing etiologies in infants. Clinical study samples collected at the University of Wisconsin–Madison describe 41 nearly complete genome sequences representing 21 RV-C genotypes.
Highlights
Human rhinovirus (RV) isolates from the RV-C species are recently discovered infectious agents that are closely linked to asthma and wheezing etiologies in infants
Strains are assigned to common species if they share Ͼ70% amino acid identity in the P1, 2C, and 3CD regions
Isolates are further subdivided into numeric genotypes that respect the historic naming system, but rely almost entirely on sequence comparisons of the VP1 or VP4/VP2 coding sequences
Summary
Human rhinovirus (RV) isolates from the RV-C species are recently discovered infectious agents that are closely linked to asthma and wheezing etiologies in infants. A full set of RNA genome sequences for these historic types was completed in 2009 [1]. Strains are assigned to common species if they share Ͼ70% amino acid identity in the P1, 2C, and 3CD regions.
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