Genome Sequences of Clinical Vibrio cholerae Isolates from an Oyster-Borne Cholera Outbreak in Florida

Bradd J Haley,Thomas A Cebula,Rita R Colwell,Nur A Hasan,Anwar Huq,Abdul Shakur H Abdullah,Seon Young Choi

doi:10.1128/genomea.00966-13

Abstract

Between November 2010 and April 2011, 11 cases of cholera were identified and associated with the consumption of raw oysters harvested from Apalachicola Bay, Florida. The etiological agent was the ctxAB-positive Vibrio cholerae serogroup O75. The genome sequences of the isolates provide useful information and are deposited in the public genome databases.

Highlights

Between November 2010 and April 2011, 11 cases of cholera were identified and associated with the consumption of raw oysters harvested from Apalachicola Bay, Florida
Ͼ200 V. cholerae serogroups have been identified, with the majority of cholera cases being ascribed to V. cholerae serogroups O1 and O139
Recent large-scale molecular analyses of V. cholerae isolates recovered from cholera outbreaks demonstrated that a significant number of cases of cholera are caused by infection with V. cholerae non-O1 or non-O139 serogroups [1,2,3]

Summary

Introduction

Between November 2010 and April 2011, 11 cases of cholera were identified and associated with the consumption of raw oysters harvested from Apalachicola Bay, Florida. The causative agent of cholera, a gastrointestinal infection causing profuse rice water diarrhea, is known to be autochthonous to aquatic environments worldwide. Ͼ200 V. cholerae serogroups have been identified, with the majority of cholera cases being ascribed to V. cholerae serogroups O1 and O139.

Results

Conclusion