Abstract
Anelloviridae is a family of circular, single-stranded DNA viruses highly prevalent among humans. We report the genome sequence of two torque teno miniviruses found in human oral mucosa samples. Genome organization, phylogenetic analysis, and pairwise comparisons reveal that they belong to novel species within the Betatorquevirus genus.
Highlights
Anelloviridae is a family of circular, single-stranded DNA viruses highly prevalent among humans
After assembling qualityfiltered (PrinSeq; minimum quality, Ն25 phred score) sequences with CLC Genomic Workbench-6, we found 17 contigs of Ͼ2 kbp that showed BLASTx similarities to anelloviruses, including two circular genomes with best BLAST similarities to viruses from the Betatorquevirus genus
The second one, TTMV_ALA22, was attained with ϫ18 coverage from an oral ulcer sample and spans 2,914 nucleotides with 38.37% GϩC contents. These genome sizes and % GϩC contents are in the range of those reported for available Betatorquevirus [1]
Summary
Anelloviridae is a family of circular, single-stranded DNA viruses highly prevalent among humans. Anelloviridae is a highly divergent family of viruses with circular single-stranded DNA genomes. Three genera of anelloviruses are able to infect humans: torque teno virus (TTV; Alphatorquevirus), torque teno minivirus (TTMV; Betatorquevirus), and torque teno minivirus (TTMDV; Gammatorquevirus), with genome sizes of 3.8 to 3.9 kb, 2.8 to 2.9 kb, and 3.2 kb, respectively [1].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
