Abstract
Streptomyces albulus PD-1, a productive strain for epsilon-poly-l-lysine and poly-l-diaminopropionic acid, was isolated from soils. We present the genome sequence of S. albulus PD-1, which may provide abundant information regarding the production of epsilon-poly-l-lysine and poly-l-diaminopropionic acid.
Highlights
Streptomyces albulus PD-1, a productive strain for epsilon-poly-L-lysine and poly-L-diaminopropionic acid, was isolated from soils
Unlike other -PL producers, S. albulus PD-1 is capable of producing an additional amino acid oligomer with antimicrobial activity, poly-L-diaminopropionic acid, during fermentation [6]
It is interesting to explore the genetic composition of S. albulus PD-1 to help account for its physiological superiority in terms of -PL production and the mechanism leading to by-product generation
Summary
Streptomyces albulus PD-1, a productive strain for epsilon-poly-L-lysine and poly-L-diaminopropionic acid, was isolated from soils. Composed of L-lysine residues linked by bonds between the ␣-carboxyl and -amino groups, -PL can be biosynthesized by Streptomycetaceae and ergot fungi [2, 3]. The most prominent feature of -PL is its antimicrobial activity against a spectrum of microorganisms, including bacteria, fungi, and particular viruses [4]. Streptomyces albulus is the most common -PL-producing species.
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