Abstract
Det7 is a Myoviridae bacteriophage that gains entry into its Salmonella enterica serovar Typhimurium host cells by adsorbing to O-antigen polysaccharide. We report here the complete 157,498-bp sequence of its genome. Det7, together with its Vi01-like relatives, are distantly related to phage T4.
Highlights
Det7 is a Myoviridae bacteriophage that gains entry into its Salmonella enterica serovar Typhimurium host cells by adsorbing to O-antigen polysaccharide
The circular sequence assembly and the similarity of its large terminase subunit (TerL) (32% identical and 48% similar amino acids) to those of phage T4 strongly suggest that Det7 virion DNA is terminally redundant and circularly permuted as the result of a headful packaging mechanism [4]
We identified 210 predicted protein-coding genes in the Det7 genome, 61 of which have a predicted function, as well as five tRNA genes, four of which have products that should recognize the AUG (Met), AAC (Asn), UAC (Tyr), and AGC (Ser) codons
Summary
Det7 is a Myoviridae bacteriophage that gains entry into its Salmonella enterica serovar Typhimurium host cells by adsorbing to O-antigen polysaccharide. The virulent double-stranded DNA (dsDNA) bacteriophage Det7 infects Salmonella enterica serovar Typhimurium. Its tail baseplate has numerous brushy protrusions, suggesting the presence of a number of host receptor-binding tailspikes.
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