Abstract

Bacteriophage (phage) therapy is expected to become an alternative therapy for Pseudomonas aeruginosa infections. P. aeruginosa phage KPP23 is a newly isolated phage belonging to the family Siphoviridae and may be a therapeutic phage candidate. We report its complete genome, which comprises 62,774 bp of double-stranded DNA containing 95 open reading frames.

Highlights

  • Bacteriophage therapy is expected to become an alternative therapy for Pseudomonas aeruginosa infections

  • Phage therapy is expected to be useful as an alternative therapeutic measure in the treatment of drugresistant P. aeruginosa infections [2]

  • Phage KPP23 was isolated from a water sample collected from Urado Bay, Kochi City, Kochi, Japan, using P. aeruginosa strain PA101 as the host strain [6]

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Summary

Introduction

Bacteriophage (phage) therapy is expected to become an alternative therapy for Pseudomonas aeruginosa infections. Phage therapy is expected to be useful as an alternative therapeutic measure in the treatment of drugresistant P. aeruginosa infections [2]. To satisfy the eligibility criteria for use as a therapeutic phage, the phage genome must be assessed for the absence of the genes associated with lysogeny, pathogenicity, and drug resistance [3, 4]. A virulent Pseudomonas phage belonging to the family Siphoviridae is proposed as a therapeutic phage [5].

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