Abstract
This study describes the near-full-length genome deep sequencing of two HIV-1 subtype D strains identified in blood donors in Rio de Janeiro, Brazil, in what seems to have been a small restricted subtype D epidemic in the country.
Highlights
This study describes the near-full-length genome deep sequencing of two HIV-1 subtype D strains identified in blood donors in Rio de Janeiro, Brazil, in what seems to have been a small restricted subtype D epidemic in the country
HIV-1 subtype D viruses were first isolated from the peripheral blood lymphocytes in 1983 in patients from the Democratic Republic of the Congo (DRC) [2]
There have been only sporadic cases with subtype D infection detected in the Rio de Janeiro (RJ) state [4,5,6,7], but none were comprehensively sequenced
Summary
This study describes the near-full-length genome deep sequencing of two HIV-1 subtype D strains identified in blood donors in Rio de Janeiro, Brazil, in what seems to have been a small restricted subtype D epidemic in the country. Most of these infections are caused by HIV-1 subtype B, except in the southern region, where subtype C prevails [1]. HIV-1 subtype D viruses were first isolated from the peripheral blood lymphocytes in 1983 in patients from the Democratic Republic of the Congo (DRC) [2]. Subtype D was reported from Brazil in a dually infected individual in 1996 [3].
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