Abstract
This review summarizes various polyherbal formulations investigated for antidepressant activity in preclinical and clinical studies. Ayurveda, an alternative medical system from India, employs both single herbs and polyherbal formulations to enhance therapeutic efficacy. Evidence suggests that whole herb extracts can be more potent than isolated compounds. Polyherbal formulations, combining multiple herbs with various active compounds, aim to maximize therapeutic effects and safety. This review compiles data from published research to provide insights for future studies and potential development of effective, marketable antidepressant formulations derived from natural sources.
Published Version
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