Abstract
This chapter discusses fetal and neonatal fatality in rat hybrids from mothers stimulated with paternal skin. The following are the reasons for the fetus not habitually provoking an immunological reaction from its mother: (1) there is an anatomical separation of fetus from its mother, (2) the fetus is not antigenically mature, and (3) the pregnant mother is immunologically indolent or inert, either in general or specifically with regard to the histocompatibility antigens of her fetus. The placentas of the stillborn fetuses differ from the normal placentas of the control group. These placentas show, at the limit of the decidua and trophoblast, a zone of diffuse necrosis, fibrin deposition surrounded by an acute exudates, which is mainly composed of polymorphonuclear neutrophils. No bacteria can be identified with Gram stain.
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