Abstract
In recent years, fat grafting has become a popular method for clinically correcting soft tissue deformities. In order to increase fat graft viability a variety of modifications have been made to current grafting procedures including cell-assisted lipotransfer (CAL), structural fat grafting, fat grafting mixed with adipose stem cells (ASCs), fat grafting mixed with platelet rich plasma (PRP) and fat grafting mixed with both ASCs and PRP; however, the persistence of the grafts after transplantation remains inconsistent. In this review, the biological fundamentals of lipotransfer procedures are discussed, the current progress of clinical fat grafting applications in plastic and reconstructive surgery is summarized, and the challenges facing fat transplantation are outlined.
Highlights
Successes and ChallengesReceived date: 22 October 2015; Accepted date: 29 October 2015; Published date: 31 October 2015
The first use of free autologous fat transplantation in a clinical setting was performed by Dr Gustav Neuber in 1893
Fat grafting is utilized as a therapeutic method for the treatment of soft tissue volume loss due to aging [5], infection [6], various types of trauma [7,8], idiopathic abnormalities [9], tumor resection [10] and many other causes of soft tissue deficiency resulting in asymmetry or contour irregularity [11,12,13,14]
Summary
Received date: 22 October 2015; Accepted date: 29 October 2015; Published date: 31 October 2015.
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