Abstract

Extraskeletal osteosarcoma is a rare mesenchymal malignancy arising in soft tissue that produces osteoid, neoplastic bone, or chondroid material without demonstrable attachments to bone or periosteum. We report an instructive case of extraskeletal osteosarcoma in a 42-year-old woman recognized following acute traumatic injury of her left thigh.

Highlights

  • Extraskeletal osteosarcoma (ESOS) is a rare malignant mesenchymal neoplasm that produces osteoid, located in the soft tissues without skeletal or periosteal attachment [1,2,3,4,5]

  • We report an instructive case of extraskeletal osteosarcoma in a 42-year-old woman recognized following acute traumatic injury of her left thigh

  • Extraskeletal osteosarcoma (ESOS) is a high-grade malignant mesenchymal soft tissue neoplasm composed of neoplastic cells that produce osteoid, neoplastic bone or chondroid matrix and has a clinically aggressive course [3, 5, 14, 15]

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Summary

Introduction

Extraskeletal osteosarcoma (ESOS) is a rare malignant mesenchymal neoplasm that produces osteoid, located in the soft tissues without skeletal or periosteal attachment [1,2,3,4,5]. We report a 42-year-old woman who presented with clinical, imaging and pathological features of osteoblastic extraskeletal osteosarcoma after a 3-month-episode of trauma of her left thigh. There was a non-tender, well-circumscribed, fixed, elastic-firm soft tissue mass measuring 30 cm x 24 cm and adhering to the deep fascia with shiny skin arising from the posterior surface of the left thigh up to the gluteal fold. Extraskeletal Osteosarcoma in the Thigh Recognized Following Acute Traumatic Injury: A Case Report and Review of the Literatu re Figure 1: Clinical aspect of the tumor after 3 months of onset It was a well-circumscribed, fixed, elastic-firm soft tissue mass adhering to the deep fascia with shiny skin and arising from the posterior surface of the left thigh up to the gluteal fold. The patient died at the ninth month (M9) after the onset of the first symptoms which correspond to the fifth month (M5) post diagnosis of extraskeletal osteosarcoma

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