Abstract
Objective To analyze the use of proton pump inhibitors(PPIs) in the perioperative period of Zhoushan Hospital, thus to make appropriate management regulations for the clinical application of PPIs. Methods From September 2016 to October 2016, the use of PPIs in 614 surgical patients of Zhoushan Hospital were statistically analyzed.The rationality of the indications, drug use, drug administration, dosage, time, course of treatment, combined medication were analyzed. Results In 614 cases, there were 341 reasonable, unreasonable 273, the failure rate was 44.46%(273/614). The main manifestations in the non indication of medication and medication course of treatment was too long. Conclusion There are many unreasonable phenomena in the course of clinical use of PPIs.Hospital and clinical pharmacists should strengthen supervision and management of the use of PPIs. Key words: Proton pump inhibitor; Perioperative period; Stress ulcer; Rational use; Evaluation studies; Inappropriate prescribing
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