Abstract
28Jul 2016 Essential Protein Identification from Protein Networks Using Topological and Biological Properties. Fathima Shabnam C B and Sminu Izudheen. Department of Computer Science and Information Systems,Mahatma Gandhi University, India. Department of Computer Science and Information Systems,Mahatma Gandhi University, India.
Highlights
Essential proteins play a very important decisive role in the survival of a cellular organisms
Need for identifying essential proteins are increasing for its contribution to the field of drug analysis and synthetic biology is very huge
As far as synthetic biology is concerned its discovery is helpful in drug design(Clatworthy et al) and identifying anomalies causing various diseases (Furney et al,2006)
Summary
Essential proteins play a very important decisive role in the survival of a cellular organisms. Essential Protein Identification from Protein Networks Using Topological and Biological Properties. Centrality methods were the first used to identify essential proteins. Due to its high sensitivity towards network accuracy much more efficient methods which included the biological properties were developed.
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