Abstract
Background and Aim: Previous studies on heart response rate (HRR) were conducted in diabetic patients. This study aims to evaluate HRR in end-stage renal disease (ESRD) patients and its correlation with myocardial perfusion imaging (MPI) findings and patients’ prognosis. Materials and Methods: The present study was conducted on patients with chronic kidney disease (CKD) who visited Shahid Hasheminejad Hospital between October 1, 2011, and September 30, 2019. Before the stress test, the patient was asked to rest in a supine position for 3 minutes while an electrocardiogram, blood pressure, and heart rate were recorded. Dipyridamole was then administered as an infusion with a dose of approximately 0.56 mg/kg of the patient’s monitoring of the electrocardiogram. The patient’s heart rate was recorded at 2-minute intervals after the start of the dipyridamole injection. Three minutes after the completion of the dipyridamole injection, radiopharmaceutical was injected. Finally, the findings of the myocardial perfusion scan were analyzed. Results: The summed stress score (SSS), and summed rest score (SRS) had a significant relationship with the female gender and ejection fraction (EF) with the male gender (P<0.05). These results were not significantly related to patients’ age and disease history (P>0.05). No significant difference was observed in the incidence of blunted HRR in patients with cardiac events by age, gender, and renal disease condition (P>0.05). Conclusion: The frequency of blunted HRR in patients with CKD based on various variables was determined for the first time in the country in the present study, which can be an introduction for future research.
Published Version
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