Effects of noninvasive ventilation combined with bronchoalveolar lavage in patients with AECOPD with respiratory failure

Abstract

Objective To investigate the application effects of noninvasive ventilation combined with bronchoalveolar lavage in patients with AECOPD with respiratory failure. Methods 70 patients with AECOPD and respiratory failure were chosen, and they were divided into control group and observation group, both two groups were treated with routine treatment, the control group combined with noninvasive ventilation, the observation group combined with bronchoalveolar lavage on the basis of the control group.Blood gas index, intubation rate, hospital stay and time of invasive ventilation between the two group were compared. Results After treatment, PaO2 and PaCO2 in the control group were (61.20±11.23)mmHg, (56.27±15.42)mmHg, which in the observation group were (73.04±8.58)mmHg, (47.25±11.18)mmHg.PaO2 and PaCO2 of the two groups were improved compared with before treatment, which of the observation group were better than the control group, the differences were statistically significant(t=4.956, 2.802, all P 0.05). Invasive ventilation time, hospital stay in the control group were (8.19±3.92)d, (10.43±4.11)d, which were higher than (6.21±1.43)d, (8.30±1.68)d in the observation group, the differences were statistically significant(t=2.807, 2.838, all P<0.05). Conclusion Noninvasive ventilation combined with bronchoalveolar lavage could effectively improve the serum index and early intubation rate, and with short invasive ventilation time and hospital stay, it is worth promoting. Key words: Pulmonary disease, chronic obstructive; Respiratory failure; Noninvasive ventilation; Bronchoscopy