Abstract
Objective To explore the effects of maternal allergy symptoms on the cytokine level of umbilical cord blood of neonates.Methods A cross sectional study was conducted among 136 pregnant women in Yiwu city from 1st July to 30th December,in 2012.A questionnaire on social economic charactertistics was used and blood sam-ple of pregnant women and umbilical cord blood sample were collected to detect the level of IgE,eosinophile granulo-cyte,Eotaxin,IL-9,IL-6,IL-4,IL-5,IFN-γ,IL-10.The differences between pregnant women with and without allergy symptoms were carried out.Results There were no significant differences in social and demographic characteristics between the two groups（all P〉0.05）.Pregnant women with allergy symptoms had higher IgE level（0.13 IU/mL vs 0.10 IU/Ml,Z=-2.063,P=0.039）,eosinophile granulocyte（0.39 ×109/mL vs 0.29 ×109/mL,Z=-2.548, P=0.011）,Eotaxin（66.18ng/L vs 48.35ng/L,Z=-2.144,P=0.032）,IFN-γ（927.81ng/L vs 338.65ng/L,Z=-2.051,P=0.040）,IL-10（15.59ng/L vs 11.55ng/L,Z=-2.022,P=0.043） than pregnant women without allergy symptoms in neonates′cord blood.Conclusion Maternal allergy symptoms may increase the level of IgE, eosinophile granulocyte,Eotaxin,IFN-γand IL-10 of neonates′cord blood. Key words: Anaphylaxis Fetal Blood Immunoglobulin E Cytokines
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
