Abstract

Abstract Background: Knee osteoarthritis (OA) is a common degenerative joint disease, often resulting from wear-and-tear and articular cartilage loss. This condition frequently leads to significant pain and physical limitations, affecting the quality of life, particularly in older adults. Objective: To determine the effectiveness of exercise combined with Kinesio tape (KT) and wedge insoles on pain and physical limitations in patients with grade 3 knee osteoarthritis. Methods: A randomized clinical trial was conducted on a sample of 60 participants diagnosed with grade 3 knee OA. Participants were randomly divided into two groups of 30 each using a sealed envelope method. Group A received exercise, KT, and wedge insoles, while Group B received exercise and KT only. Both groups underwent 24 sessions over eight weeks, with three sessions per week. The interventions included electrotherapeutic modalities, strengthening exercises for the quadriceps and hamstrings, and KT application. Pain and physical function were measured using the Visual Analogue Scale (VAS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) at baseline, the fourth week, and the eighth week. Data were analyzed using SPSS version 25, with the Friedman test assessing within-group effects and the Mann-Whitney U test evaluating between-group differences. Statistical significance was set at p < 0.05. Results: Group A consisted of 12 males (40%) and 18 females (60%), with a mean age of 52.33 ± 6.34 years. Group B had 10 males (33.3%) and 20 females (66.7%), with a mean age of 52.94 ± 5.75 years. Significant improvements were observed within both groups in VAS and WOMAC scores (p < 0.05). Post-treatment, Group A demonstrated greater improvements in VAS (mean difference = 2.5, p = 0.000) and WOMAC (mean difference = 15.3, p = 0.000) compared to Group B. Conclusion: Both exercise combined with KT and exercise combined with KT and wedge insoles were effective in reducing pain and improving physical function in patients with grade 3 knee osteoarthritis. However, the combination of exercise and KT without wedge insoles produced superior effects. These findings suggest that KT, as an adjunct to exercise therapy, may provide additional benefits for managing knee OA. Keywords: Knee Osteoarthritis, Kinesio Tape, Wedge Insole, Pain Management, Physical Function, Randomized Clinical Trial, Non-Surgical Treatment, Electrotherapeutic Modalities, Strengthening Exercises, Visual Analogue Scale, WOMAC

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