Abstract

Objective To explore the effects of cognitive behavioral intervention on fear of disease progression and negative emotionin patients with glioma. Methods A total of 60 eligible patients with glioma who were treated in neurosurgery department of the First Affiliated Hospital of Zhengzhou University from January to October 2016 were randomly divided into experimental group (n=30) and control group (n=30) according to random number table. The control group received routine care, and the experimental group patients received cognitive behavioral intervention for 12 weeks on the basis of routine care. Cognitive assessment and cognitive reconstruction were performed to achieve cognitive intervention by interviews, lectures and other forms. Behavioral intervention was achieved by musical relaxation training and personalized exercise programs for the patients. The patients were evaluated with the Fear of Progression Questionnaire-Short Form (FoP-Q-SF) , Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) on the admission day, 1 week after surgery and 3 months after surgery to compare the fear of disease progression and negative emotion of the two groups. Results Repeated measurement analysis of variance showed that with the extension of time, the anxiety and depression scores of the two groups were decreased, and the score of the observation group was lower than that of the control group. The differences were statistically significant (P 0.05) . The score of the observation group was significantly lower than that of the control group at 3 months after intervention, with statistical difference (P<0.05) . Conclusions There were different degrees of fear of progression and negative emotions in patients with glioma at different stages of disease. Cognitive behavioral intervention can effectively alleviate the fear of disease progression, anxiety and depression in patients with glioma, and it is worthy of clinical promotion. Key words: Glioma; Anxiety; Depression; Fear of progression; Cognitive behavioral intervention

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