Effect of remifentanil combined with propofol intravenous anesthesia on hemorheology and perioperative hypoxemia in patients undergoing painless artificial abortion

Abstract

Objective To investigate the effect of remifentanil combined with propofol intravenous anesthesia on hemorheology and perioperative hypoxemia in patients undergoing painless artificial abortion. Methods Eighty-eight patients undergoing painless artificial abortion were divided into groups according to the random number table method, with 44 cases in each group. The control group was given propofol anesthesia, and the observation group was given remifentanil and propofol anesthesia. The recovery time of two groups, the degree of pain, the dosage of propofol, analgesic effect, hypoxemia and adverse reactions were statistically analyzed, and the blood rheology (plasma viscosity, whole blood high cut, low shear viscosity and change) at the time of administered (T0), surgery (T1), open your eyes (T2) were compared. Results The degree of pain, the dosage of propofol in the observation group were significantly lower than those of the control group, and the differences were significant (P 0.05). Compared with the control group, the levels of hemorheology were significantly lower in the observation group at T1 and T2 (P<0.05). The incidence of hypoxemia in the observation group[4.55% (2/44)] was lower than that in the control group[9.09%(4/44)], the difference was significant (P<0.05). The incidence of adverse reaction in the observation group was 9.09% (4/44), which was lower than that of the control group [27.28%(12/44)], and the difference was significant (P<0.05). Conclusions Remifentanil combined with propofol anesthesia can effectively shorten the recovery time of patients with painless artificial abortion, relieve the pain degree and reduce the dosage of propofol and incidence of hypoxemia. It can improve the indexes of hemorheology. The analgesic effect is significant, and the safety is high. Key words: Remifentanil; Propofol; Intravenous anesthesia; Painless artificial abortion; Hemorheology; Hypoxemia