Comparison of dyclonine hydrochloride mortar and oxybuprocaine hydrochloride gel for painless artificial abortion

Abstract

Objective To compare the efficacy of dyclonine hydrochloride mortar and oxybuprocaine hydrochloride gel combined with intravenous propofol in painless artificial abortion. Methods Sixty subjects accepting painless artificial abortion were randomly divided into dyclonine group and oxybuprocaine group, 30 cases in each group. The subjects were intravenously injected with propofol to fall asleep, then dyclonine hydrochloride mortar and oxybuprocaine hydrochloride gel were respectively applied to the cervical smear and the cervical tube injection after disappearance of eyelash reaction. Artificial abortion was performed after 1 min. HR, BP, RR, SpO2, physical reaction, cervical relaxation, propofol dosage, intraoperative amount of bleeding and awaking time were recorded and compared in the two groups. Results There were no significant difference in blood pressure, heart rate and SpO2 between the two groups before and during the anesthesia (P>0.05). The cases of motor responses, cervical relaxation, propofol dosage and awaking time were lower in dyclonine group than those in oxybuprocaine group (P 0.05). Conclusion Dyclonine hydrochloride mortar applied locally combined with intravenous propofol is of better analgesic effect and less propofol dosage compared with oxybuprocaine hydrochloride gel combined with intravenous propofol in painless artificial abortion. Key words: Hydrochloric acid dyclonine; Oxybuprocaine; Propofol; Abortion, induced