Abstract
Objective To analyze the therapatic effect of nasal endoscopic radiofrequency ablation on the stress response and ventilation function in children with obstructive sleep apnea-hypopnea syndrome(OSAHS). Methods Seventy-eight children with OSAHS were selected and randomly divided into observation group (39 cases) and control group (39 cases). The control group was treated by adenoid curettage and tonsillectomy by dissection, the observation group was treated by nasal endoscopic low temperature plasma radiofrequency ablation. The total efficiency, intraoperative the blood loss, visual analogue scale (VAS) score postoperative 1 d and 3 d, serum stress index [glutathione (GSH) malondialdehyde (MDA), superoxide dismutase (SOD) and nitrotyrosine (3-NT)] level were compared between the two groups. The ventilation function [time length of nocturnal oxygen saturation <90% (SLT90%), respiratory disturbance index (AHI), the longest apnea time (LAT) and oxygen desaturation index (ODI)] were detected before operation and after 6 months of operation in the two groups by polysomnography sleep time. Results The total efficiency in the observation group(94.87%)was higher than that in the control group (76.92%), the difference was significant (P 0.05); compared with the control group, LAT, AHI, ODI and SLT 90% after 6 months of operation in the observation group were significantly lower, the differences were significant (P<0.05). Conclusions Nasal endoscopic low temperature plasma radiofrequency ablation in the treatment of children with OSAHS can reduce intraoperative blood loss, alleviate pain and stress reaction of children after operation, and improve ventilation function. Key words: Children with obstructive sleep apnea-hypopnea syndrome; Ventilation function; Stress response; Radiofrequency ablation
Published Version
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