Abstract

Objective To study the effect of atravastain on vascular endothelium in patients with T2 DM. Methods 180 cases of T2 DM were detected in patients with blood Sugar、 Blood pressure、 Blood lipids、NO、ET、PGF1a. At the same time we used high differentiate ultrasonic to dect FMD% 、GTN%. Results Patients treated with atravastain whose NO、 PGF1a indreased obviously, ET decreased significantly, FMD% improved, GTN% no distint change. Conclusion Atravastain by reducing LDL、ET、HDL、NO 、PGF1a means to achieve the protection of vascular endothelium in patients with T2DM, reduce the incidence of diseases associate with ECD. Key words: Atravastain;  T2 DM;  Function of vascular endothelium

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