Abstract
Clostridium botulinum is important for food safety and studies of neurotoxins associated with human botulism. We present the draft genome sequences of two strains belonging to group II type B: one collected from Pacific Ocean sediments (DB-2) and another obtained during a botulism outbreak (KAPB-3).
Highlights
Clostridium botulinum is important for food safety and studies of neurotoxins associated with human botulism
Botulism is characterized by a wide range of symptoms from vomiting and gastrointestinal distress to cranial nerve palsies that may progress to complete flaccid paralysis and death due to respiratory failure (3)
Group II is nonproteolytic and organized into three serotypes (A, B, or F) that are distinguished by the botulinum neurotoxin produced (5)
Summary
Clostridium botulinum is important for food safety and studies of neurotoxins associated with human botulism. Clostridium botulinum is a Gram-positive, anaerobic bacterium that is present naturally in soils and sediments around the world (1). C. botulinum produces a highly potent neurotoxin that may cause botulism when ingested (2).
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