Abstract

Clostridium botulinum is important for food safety and studies of neurotoxins associated with human botulism. We present the draft genome sequences of two strains belonging to group II type B: one collected from Pacific Ocean sediments (DB-2) and another obtained during a botulism outbreak (KAPB-3).

Highlights

  • Clostridium botulinum is important for food safety and studies of neurotoxins associated with human botulism

  • Botulism is characterized by a wide range of symptoms from vomiting and gastrointestinal distress to cranial nerve palsies that may progress to complete flaccid paralysis and death due to respiratory failure (3)

  • Group II is nonproteolytic and organized into three serotypes (A, B, or F) that are distinguished by the botulinum neurotoxin produced (5)

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Summary

Introduction

Clostridium botulinum is important for food safety and studies of neurotoxins associated with human botulism. Clostridium botulinum is a Gram-positive, anaerobic bacterium that is present naturally in soils and sediments around the world (1). C. botulinum produces a highly potent neurotoxin that may cause botulism when ingested (2).

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