Abstract
We report the draft genome sequences of PKUSS-HG01 and PKUSS-LG01, two clinical isolates of Streptococcus mutans from human dental plaque. The genomics information will facilitate the study of the mechanisms of pathogenicity and evolution of S. mutans.
Highlights
We report the draft genome sequences of PKUSS-HG01 and PKUSS-LG01, two clinical isolates of Streptococcus mutans from human dental plaque
S. mutans metabolizes a variety of carbohydrates, generating organic acid in dental plaque
Functional annotations were performed by search against the NCBI nr, Swiss-Prot (10), Clusters of Orthologous Groups (COG) (11), KEGG (12), and InterProScan (13) databases
Summary
We report the draft genome sequences of PKUSS-HG01 and PKUSS-LG01, two clinical isolates of Streptococcus mutans from human dental plaque. Streptococcus mutans is a Gram-positive organism that is the primary causative agent in the formation of dental caries in humans. S. mutans metabolizes a variety of carbohydrates, generating organic acid in dental plaque. The acidic environment results in mineral loss on the surface of teeth and eventually causes tooth decay (1).
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