Draft Genome Sequences of Six Actinobacillus pleuropneumoniae Serotype 8 Brazilian Clinical Isolates: Insight into New Applications.

Monalessa Fábia Pereira,Fabíola Marques De Carvalho,Ana Tereza Ribeiro De Vasconcelos,Luiz Gonzaga Paula De Almeida,Rangel Celso Souza,Ciro César Rossi,Denise Mara Soares Bazzolli

doi:10.1128/genomea.01585-14

Abstract

Actinobacillus pleuropneumoniae is the causative agent of swine pleuropneumonia, a highly contagious disease associated with pigs of all ages that results in severe economic losses to the industry. Here, we report for the first time six genome sequences of A. pleuropneumoniae clinical isolates of serotype 8, found worldwide.

Highlights

Actinobacillus pleuropneumoniae is the causative agent of swine pleuropneumonia, a highly contagious disease associated with pigs of all ages that results in severe economic losses to the industry
We sequenced six serotype 8 A. pleuropneumoniae clinical isolates that are persistent in farms in southeastern Brazil and present different virulence degrees [6]
Contigs were reordered with Mauve using A. pleuropneumoniae JL03 as the reference genome

Summary

Introduction

Actinobacillus pleuropneumoniae is the causative agent of swine pleuropneumonia, a highly contagious disease associated with pigs of all ages that results in severe economic losses to the industry. Serotype 8 isolates, the most widespread in southeastern Brazil [3], display high cytotoxic activity and are generally responsible for low mortality but high morbidity. This serotype is dominant in other pig-producing countries, such as Mexico and the United Kingdom [4, 5].

Results

Conclusion