Abstract
The draft genome sequences of six Colombian Helicobacter pylori strains are presented. These strains were isolated from patients from regions of high and low gastric cancer risk in Colombia and were characterized by multilocus sequence typing. The data provide insights into differences between H. pylori strains of different phylogeographic origins.
Highlights
Helicobacter pylori is a Gram-negative, microaerophilic, helixshaped bacterium that colonizes the stomachs of at least half of the world’s human population (1)
We announce the genome sequencing of six strains of Helicobacter pylori. These strains were isolated from three patients from the low-gastric-cancer-risk region of Tumaco, Colombia, and three patients from the high-gastric-cancer-risk region of Pasto, Colombia
These strains have been previously classified by multilocus sequence typing (MLST) and found to be of African (PZ5004 and PZ5024) and of European (PZ5026, PZ5056, PZ5080, and PZ5086) origins (3)
Summary
Helicobacter pylori is a Gram-negative, microaerophilic, helixshaped bacterium that colonizes the stomachs of at least half of the world’s human population (1). H. pylori can persist in the human stomach without health consequences, though it is a risk factor for chronic gastritis, gastric or duodenal ulcers, and gastric cancer (2). We announce the genome sequencing of six strains of Helicobacter pylori.
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