Abstract

Escherichia coli O157:H7 is a major etiologic agent of diseases in humans that cause diarrhea, hemorrhagic colitis, and hemolytic-uremic syndrome. Here, we report the draft genome sequences of two strains isolated from cattle that had high levels of Shiga toxin 2 and high lethality in mice.

Highlights

  • Escherichia coli O157:H7 is a major etiologic agent of diseases in humans that cause diarrhea, hemorrhagic colitis, and hemolytic-uremic syndrome

  • Escherichia coli O157:H7 is the etiologic agent of hemolyticuremic syndrome

  • This is the leading cause of chronic renal failure in children in Argentina and several other countries [1]. This bacterium produces Shiga toxin (Stx) types 1 and 2 [2, 3], which are responsible for systemic damage

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Summary

Introduction

Escherichia coli O157:H7 is a major etiologic agent of diseases in humans that cause diarrhea, hemorrhagic colitis, and hemolytic-uremic syndrome. Escherichia coli O157:H7 is the etiologic agent of hemolyticuremic syndrome. This is the leading cause of chronic renal failure in children in Argentina and several other countries [1]. This bacterium produces Shiga toxin (Stx) types 1 and 2 [2, 3], which are responsible for systemic damage.

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Conclusion

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