Abstract
Here, we report the draft genome sequences of 63 Pseudomonas aeruginosa isolates, recovered in culture of sputum from 15 individuals with cystic fibrosis (CF) receiving care in a single CF care center over a 13-year period. These sequences add value to studies of within-host evolution of bacterial pathogens during chronic infection.
Highlights
We report the draft genome sequences of 63 Pseudomonas aeruginosa isolates, recovered in culture of sputum from 15 individuals with cystic fibrosis (CF) receiving care in a single CF care center over a 13-year period
Recent studies have noted considerable genetic variation among isolates serially recovered from CF patients during the course of chronic infection [2,3,4]
This genetic variation may confound genotyping of P. aeruginosa isolates, which is important for monitoring potential interpatient spread of specific strains in this patient population
Summary
We report the draft genome sequences of 63 Pseudomonas aeruginosa isolates, recovered in culture of sputum from 15 individuals with cystic fibrosis (CF) receiving care in a single CF care center over a 13-year period. Recent studies have noted considerable genetic variation among isolates serially recovered from CF patients during the course of chronic infection [2,3,4]. This genetic variation may confound genotyping of P. aeruginosa isolates, which is important for monitoring potential interpatient spread of specific strains in this patient population. We determined the whole-genome sequences of 63 P. aeruginosa isolates cultured from 15 adult CF patients during a period of 13 years.
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