Abstract

We report here the draft genome sequences of 11 strains of Staphylococcus epidermidis, a common bacterium inhabiting the skin of humans and other animals. These isolates, obtained from five mouse species, provide valuable information on the native Staphylococcus spp. of this important model organism and form a basis for studying host-bacterial interactions in their natural environment.

Highlights

  • We report here the draft genome sequences of 11 strains of Staphylococcus epidermidis, a common bacterium inhabiting the skin of humans and other animals

  • Staphylococcus epidermidis, on the other hand, is of critical importance, as it is the most common source of medical device-associated infections (5), but at the same time, it is capable of inhibiting S. aureus colonization in human nasal cavities (6)

  • We recently discovered Staphylococcus to contain important members of the native mouse skin microbiota influencing susceptibility to autoimmune skin blistering (9)

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Summary

Introduction

We report here the draft genome sequences of 11 strains of Staphylococcus epidermidis, a common bacterium inhabiting the skin of humans and other animals. The genus Staphylococcus contains important members of the human skin microbiome (1). Staphylococcus aureus is so far the main species of interest, as it is a major source of nosocomial infections and can afflict numerous organs (2). Staphylococcus epidermidis, on the other hand, is of critical importance, as it is the most common source of medical device-associated infections (5), but at the same time, it is capable of inhibiting S. aureus colonization in human nasal cavities (6).

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