Abstract
Dehalococcoides mccartyi strain SG1, isolated from digester sludge, dechlorinates polychlorinated biphenyls (PCBs) to lower congeners. Here we report the draft genome sequence of SG1, which carries a 22.65 kbp circular putative plasmid.
Highlights
Dehalococcoides mccartyi strain SG1, isolated from digester sludge, dechlorinates polychlorinated biphenyls (PCBs) to lower congeners
The obligate organohalide-respiring Dehalococcoides mccartyi strains in both microcosms [1,2,3,4] and pure cultures [5,6,7] have been identified to be capable of dechlorinating PCBs in distinct patterns
Most reductive dehalogenases (RDases) genes are located in the high plasticity regions (HPRs) of chromosomes [7, 9, 10], suggesting that their horizontal acquisition is possibly through temperate bacteriophages or plasmids
Summary
Dehalococcoides mccartyi strain SG1, isolated from digester sludge, dechlorinates polychlorinated biphenyls (PCBs) to lower congeners. The obligate organohalide-respiring Dehalococcoides mccartyi strains in both microcosms [1,2,3,4] and pure cultures [5,6,7] have been identified to be capable of dechlorinating PCBs in distinct patterns. Populations of this bacterial group have small circular chromosomes of around 1.5 Mbp, yet each carries a suite of 10 to 36 different rdhA genes encoding reductive dehalogenases (RDases) for catalyzing the chlorine removal [8]. Most RDase genes are located in the high plasticity regions (HPRs) of chromosomes [7, 9, 10], suggesting that their horizontal acquisition is possibly through temperate bacteriophages or plasmids.
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