Draft Genome Sequence of Non-O1 and Non-O139 Vibrio cholerae Strain VCC19.

Pablo Caracciolo Gomes De Sá,Maria Helena Matté,Rommel Thiago Jucá Ramos,Larissa Maranhão Dias,Rafael Azevedo Baraúna,Diego Assis Das Graças,Adriana Ribeiro Carneiro,Jaqueline Conceição Meireles Gomes,Elayse Maria Hachich,Miriam Lopes Da Silva,Artur Silva,Maria Ines Zanolli Sato,Glavur Rogério Matté,Jorianne Thyeska Castro Alves,Adonney Allan De Oliveira Veras

doi:10.1128/genomea.01094-14

Abstract

Vibrio cholerae O1 is the causative agent of cholera and is ubiquitous in the aquatic environment, while V. cholerae strains non-O1 and non-O139 are recognized as causative agents of sporadic and localized outbreaks of diarrhea. Here, we report the complete sequence of a non-O1 and non-O139 V. cholerae strain (VCC19), which was isolated from the environment in Brazil. The sequence includes the integrative conjugative element (ICE). This paper is the first report of the presence of such an element in a V. cholerae strain isolated in Brazil.

Highlights

Vibrio cholerae O1 is the causative agent of cholera and is ubiquitous in the aquatic environment, while V. cholerae strains non-O1 and non-O139 are recognized as causative agents of sporadic and localized outbreaks of diarrhea
V. cholerae O1 is the causative agent of cholera, which is a diarrheic disease that is produced due to the presence of a virulence gene cassette, which is recognized as the main factor that contributes to the pathogenicity in the toxigenic strains of O1 and O139 serotypes [1]
Studies have demonstrated that non-O1 and non-O139 V. cholerae strains may be involved in the emergence of V. cholerae O139 by the acquisition of virulence genes from V. cholerae O1 [1]

Summary

Introduction

Vibrio cholerae O1 is the causative agent of cholera and is ubiquitous in the aquatic environment, while V. cholerae strains non-O1 and non-O139 are recognized as causative agents of sporadic and localized outbreaks of diarrhea. V. cholerae O1 is the causative agent of cholera, which is a diarrheic disease that is produced due to the presence of a virulence gene cassette, which is recognized as the main factor that contributes to the pathogenicity in the toxigenic strains of O1 and O139 serotypes [1]. Non-O1 and non-O139 V. cholerae strains are recognized as causative agents of sporadic and localized outbreaks of diarrhea.

Results

Conclusion