Abstract
Clostridium botulinum is a pathogen of concern for low-acid canned foods. Here we report draft genomes of a neurotoxin-producing C. botulinum strain isolated from water samples used for cooling low-acid canned foods at a canning facility. The genome sequence confirmed that this strain belonged to C. botulinum serotype B1, albeit with major differences, including thousands of unique single nucleotide polymorphisms (SNPs) compared to other genomes of the same serotype.
Highlights
Clostridium botulinum is a Gram-positive, spore-forming anaerobic bacterium that produces botulinum neurotoxin (BoNT) (1)
The neurotoxins produced by these organisms have been differentiated into seven serotypes, designated by the letters A through G (4)
C. botulinum is the pathogen of concern for low-acid canned foods (LACF)
Summary
Clostridium botulinum is a Gram-positive, spore-forming anaerobic bacterium that produces botulinum neurotoxin (BoNT) (1). Intoxication with the potent BoNT gives rise to the serious paralytic illness botulism in humans and is a serious concern for food safety. The neurotoxins produced by these organisms have been differentiated into seven serotypes, designated by the letters A through G (4). C. botulinum is the pathogen of concern for low-acid canned foods (LACF).
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