Abstract
<p>Candida albicans is the most common cause of fungal infections worldwide. Non-albicans Candida species play an important role in vulvovaginal candidiasis and invasive infections. Most cases of infections are endogenous. In case of patients with immune disorders this opportunistic pathogen causes both surface, systemic infections, and candidemia. Symptoms depend on the area affected. Candidiasis are treated with antimycotics; these include clotrimazole, nystatin, fluconazole, voriconazole, amphotericin B, and echinocandins. The emergence of drug resistance and the side effects of currently available antifungals are becoming a major problem in the management of Candida spp. infection.</p>
Highlights
Candidiasis is a fungal infection caused by yeasts that belong to the class Saccharomycetes
Candida albicans is the most common cause of fungal infections worldwide [24] There are over 20 species of Candida spp. yeasts that can cause infection in humans, ive most common of them are C. albicans, C. glabrata, C. krusei, C. parapsilosis and C. tropicalis
Empirical antifungal therapy is recommended when there is a suspicion of oesophagus mycosis in case of patients with impaired immune system [27]
Summary
MARTA DąBROWSKA1,2, MONIKA SIENKIEWICz1*, PAWEŁ KWIATKOWSKI3, hANNA zIELIńSKA-BLIźNIEWSKA1, MIChAŁ DąBROWSKI1. S 1Department of Allergology and Respiratory Rehabilitation, 2nd Chair of Otolaryngology, Medical University of Łódź, Poland2Department of Gynecology and Obstetrics, District hospital in Garwolin, Poland. Candida albicans is the most common cause of fungal infections worldwide. Non-albicans Candida species play an important role in vulvovaginal candidiasis and invasive infections. In case of patients with immune disorders this opportunistic pathogen causes both surface, systemic infections, and candidemia. Candidiasis are treated with antimycotics; these include clotrimazole, nystatin, luconazole, voriconazole, amphotericin B, and echinocandins. The emergence of drug resistance and the side effects of currently available antifungals are becoming a major problem in the management of Candida spp. infection
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More From: Annales Universitatis Mariae Curie-Sklodowska, sectio C – Biologia
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