Abstract
<p>Candida albicans is the most common cause of fungal infections worldwide. Invasive candidiasis comprises candidemia and deep-seated candidiasis. Most yeast invasive infections are endogenous with a high mortality. Pathogenesis of candidiasis depends on avoiding host immune responses, as well as the virulence factors of the fungus enabling colonization and invasion of tissues. Adequate source control and antifungal therapy administered within a short time is critical to get a better prognosis. The emergence of drug resistance and the side effects of currently available antifungals are becoming the major problem in the management of Candida spp. infection.</p>
Highlights
Invasive fungal infection is associated with a high mortality ranging from 29 to 90% [1]
U Patients with invasive candidiasis are often already sick from other medical conditions, so it can be dificult to know which symptoms are related to a Candida spp. infection
Mof exposure to an azole, moderately severe to severe illness. They are recommended for patients with allergy or intolerance to azoles or AmB, or high risk of infection with C. krusei or C. glabrata
Summary
MARTA DąBROWSKA1,2, MONIKA SIENKIEWICz1*, PAWEŁ KWIATKOWSKI3, hANNA zIELIńSKA-BLIźNIEWSKA1, MIChAŁ DąBROWSKI1. S 1Department of Allergology and Respiratory Rehabilitation, 2nd Chair of Otolaryngology, Medical University of Łódź, Poland 2Department of Gynecology and Obstetrics, District hospital in Garwolin, Poland
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