Abstract
ABSTRACT Case report of central giant cell lesion (CGCL) in a 32-year-old female patient, who exhibited asymptomatic increase in mandible volume and integrity of the adjacent alveolar mucosa, she was submitted to conservative treatment. The imaging exams showed radiolucent and multilocular lesion with displacement and discrete root resorption of the teeth 34 and 35. An incisional biopsy was performed and the final diagnosis of CGCL was established. The patient was submitted to biweekly applications of triamcinolone hexacetonide, showing no recurrence and exhibiting bone reintegration. Treatment of extensive lesions with intralesional corticosteroid injections has shown satisfactory effects.
Highlights
Case report of central giant cell lesion (CGCL) in a 32-year-old female patient, who exhibited asymptomatic increase in mandible volume and integrity of the adjacent alveolar mucosa, she was submitted to conservative treatment
The patient was submitted to biweekly applications of triamcinolone hexacetonide, showing no recurrence and exhibiting bone reintegration
The biological behavior of CGCL can vary from a non-aggressive lesion – in which there is no symptoms, slow growth, no cortical bone resorption or perforation – to an aggressive pathological process, exhibiting pain, paresthesia, rapid growth, root resorption and cortical perforation[5]
Summary
The central giant cell lesion (CGCL) was first described by Jaffe (1953)(1) as a “maxillary giant cell reparative granuloma”. It is an intraosseous lesion, whose etiopathogenesis remains uncertain, and is considered reactive or neoplastic. It mainly affects patients in the younger age group, between 10 and 25 years, with incidence of 2:1 in the mandible when compared to the maxilla[2,3,4]. CGCL can range from small unilocular apical lesions to large multilocular radiolucencies, involving the gnathic bones[4]. The objective of this study is to report a case of CGCL, emphasizing a conservative therapy
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Jornal Brasileiro de Patologia e Medicina Laboratorial
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
