Abstract
Hybrid lesions encompass the occurrence of different entities in one lesion. A 67-year-old woman was referred to the Oral and Maxillofacial Surgery Service for treatment of mandibular Central Giant Cell Lesion (CGCL) previously diagnosed. Intraoral examination revealed edentulism and a painless swelling extending from the alveolar ridge to the buccal vestibule with hard consistency covered by normal mucosae, with unknown duration. Panoramic radiograph revealed a large, multilocular and well-defined radiolucent lesion extending from the region of left mandibular lateral incisor teeth to right mandibular first molar with no evidence of osseous perforation. Initially, a treatment with intralesional injection of corticosteroids was performed. After 18 months of treatment, an increase in size of the osteolytic lesion was noted. An incisional biopsy was carried out and the microscopic examination revealed a unicystic ameloblastoma associated to CGCL. It was performed marsupialization and later the enucleation of residual lesion. The follow-up remains being performed. Key words:Hybrid lesion, central giant cell lesion, ameloblastoma.
Highlights
Hybrid lesions encompass elements of different pathologies in one lesion and the occurrence within the jaws are rarely reported [1]
Unicystic Ameloblastoma (UA) is a variant form that mostly occurs in a younger age group having an odontogenic cyst-like behavior
Central giant cell lesion (CGCL) was reported in association with central odontogenic fibroma (COF) [7], fibro-osseous lesions [1], and with odontogenic keratocyst [8]
Summary
Hybrid lesions encompass elements of different pathologies in one lesion and the occurrence within the jaws are rarely reported [1]. The two last exams revealed an increase of the osteolytic component of the lesion in the anterior region of mandible, extending to the left side and causing an expansion of cortical bone on intraoral clinical examination.
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