HYBRID CENTRAL GIANT CELL LESION AND AMELOBLASTOMA OF THE MANDIBLE

Abstract

Hybrid lesions encompass the occurrence of different entities in 1 lesion. A 67-year-old woman was referred to the oral and maxillofacial surgery service for treatment of mandibular central giant cell lesion (CGCL) previously diagnosed. Intra-oral examination revealed edentulism and a painless swelling extending to the buccal vestibule with hard consistency, without fluctuation and covered with normal mucosae, for an unknown period. Panoramic radiograph revealed a large, multilocular, and well-defined radiolucent lesion extending from the region of teeth #32 to #46, with no evidence of osseous perforation. Initial treatment with intralesional corticosteroids was performed. After 18 months, an increase of the osteolytic lesion extending from the anterior to the posterior left side of the mandible was noted radiographically. After incisional biopsy, the microscopic examination revealed an ameloblastoma associated with CGCL. Marsupialization was performed, and later the enucleation of the residual lesion. The follow-up is still being conducted. Hybrid lesions encompass the occurrence of different entities in 1 lesion. A 67-year-old woman was referred to the oral and maxillofacial surgery service for treatment of mandibular central giant cell lesion (CGCL) previously diagnosed. Intra-oral examination revealed edentulism and a painless swelling extending to the buccal vestibule with hard consistency, without fluctuation and covered with normal mucosae, for an unknown period. Panoramic radiograph revealed a large, multilocular, and well-defined radiolucent lesion extending from the region of teeth #32 to #46, with no evidence of osseous perforation. Initial treatment with intralesional corticosteroids was performed. After 18 months, an increase of the osteolytic lesion extending from the anterior to the posterior left side of the mandible was noted radiographically. After incisional biopsy, the microscopic examination revealed an ameloblastoma associated with CGCL. Marsupialization was performed, and later the enucleation of the residual lesion. The follow-up is still being conducted.