Abstract
All members of the lyssavirus genus cause the disease rabies. European bat lyssavirus 1 (EBLV-1) viruses are divided genetically into three groups according to geographic location and host reservoir. We report here the first genome sequence for an EBLV-1 isolated from Eptesiscus isabellinus in the Iberian Peninsula, Spain.
Highlights
In Europe, bat rabies cases are dominated by two lyssavirus species: European bat lyssavirus 1 (EBLV-1) and European bat lyssavirus 2 (EBLV-2) (1)
Analysis of EBLV-1 viruses from Eptesiscus isabellinus in the Iberian Peninsula has demonstrated that these viruses are genetically similar, yet distinct from other EBLV-1 circulating in Eptesiscus serotinus (3)
Double-stranded cDNA was synthesized from 50 ng RNA by use of a random cDNA synthesis system (Roche), according to the manufacturer’s instructions
Summary
In Europe, bat rabies cases are dominated by two lyssavirus species: European bat lyssavirus 1 (EBLV-1) and European bat lyssavirus 2 (EBLV-2) (1). EBLV-1 molecular epidemiological investigations separated the species into 2 sublineages (1a and 1b) (2). Analysis of EBLV-1 viruses from Eptesiscus isabellinus in the Iberian Peninsula has demonstrated that these viruses are genetically similar, yet distinct from other EBLV-1 circulating in Eptesiscus serotinus (3). Fullgenome sequences are available for five EBLV-1a and a single EBLV-1b virus.
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