Abstract
In addition to the eight genotypes of classic human astroviruses, seven new genotypes have been reported from two novel clades, MLB and VA. However, the epidemiology of these highly diverse astroviruses remains largely unknown. We report here the complete genome sequences of two MLB1 strains from Bhutanese children with diarrhea.
Highlights
In addition to the eight genotypes of classic human astroviruses, seven new genotypes have been reported from two novel clades, MLB and VA
In 2009, astrovirus clade MLB1 was detected during an outbreak of diarrhea in Australian children [5]
Subsequent studies revealed the presence of MLB1 among diarrheal patients in the United States, China, Hong Kong, Egypt, India, and Nigeria, complete genome sequences of this virus are only available from Australia, United States, China, and Hong Kong
Summary
In addition to the eight genotypes of classic human astroviruses, seven new genotypes have been reported from two novel clades, MLB and VA. Rotavirus is the most common cause of diarrhea, but the focus is shifting to other viruses to understand their impact since the introduction of two successful rotavirus vaccines [2, 3]. Astroviruses are responsible for 20% of diarrhea cases and have the potential for zoonosis because these highly diverse viruses infect a wide range of animals [4].
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