Abstract
Shiga toxin-producing Escherichia coli (STEC) strains are important foodborne pathogens associated with human disease. Most disease-associated STEC strains carry the locus of enterocyte effacement (LEE); however, regularly LEE-negative STEC strains are recovered from ill patients. Few reference sequences are available for these isolate types. Here, we report here the complete genome sequences for four LEE-negative STEC strains.
Highlights
Shiga toxin-producing Escherichia coli (STEC) strains are important foodborne pathogens associated with human disease
While many STEC strains associated with severe disease possess the locus of enterocyte effacement (LEE) pathogenicity island and often harbor a large EHEC virulence plasmid carrying the enterohemolysin-encoding gene, ehxA [2,3,4], sporadically, LEE-negative STEC strains are recovered from severely ill individuals [5, 6]
Only a few complete reference sequences are available for those STEC strains; we sequenced the complete genomes of four ehxA-positive LEE-negative STEC strains isolated from foods
Summary
Shiga toxin-producing Escherichia coli (STEC) strains are important foodborne pathogens associated with human disease. Shiga toxin-producing Escherichia coli (STEC) strains are major foodborne pathogens that can cause mild/bloody diarrhea and life-threatening hemolytic-uremic syndrome (HUS). While many STEC strains associated with severe disease possess the locus of enterocyte effacement (LEE) pathogenicity island and often harbor a large EHEC virulence plasmid carrying the enterohemolysin-encoding gene, ehxA [2,3,4], sporadically, LEE-negative STEC strains are recovered from severely ill individuals [5, 6].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
