Abstract
Zika virus (ZIKV) is an emerging pathogenic flavivirus currently circulating in numerous countries in South America, the Caribbean, and the Western Pacific Region. Using an unbiased metagenomic sequencing approach, we report here the first complete genome sequence of ZIKV isolated from a clinical semen sample.
Highlights
Zika virus (ZIKV) is an emerging pathogenic flavivirus currently circulating in numerous countries in South America, the Caribbean, and the Western Pacific Region
ZIKV RNA has been identified in semen from infected males, including detection at more than two months post onset of symptoms [3,4,5]
A diagnostic semen sample provided 13 days post onset of symptoms from a patient returning from Guadeloupe was identified as positive for ZIKV RNA with a high copy number
Summary
Zika virus (ZIKV) is an emerging pathogenic flavivirus currently circulating in numerous countries in South America, the Caribbean, and the Western Pacific Region. Since October 2013, an outbreak of Zika virus (ZIKV) has affected 68 countries across South America, the Caribbean, and the Western Pacific Region [1]. ZIKV RNA has been identified in semen from infected males, including detection at more than two months post onset of symptoms [3,4,5]. To date, no ZIKV sequence greater than 300 bases long from semen has been made publically available.
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